Механизмы резистентности к антибактериальным препаратам у Mycobacterium tuberculosis

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В обзоре приведены результаты исследований механизмов действия давно применяемых и новых противотуберкулезных препаратов, а также данные о новых химических соединениях — потенциальных противотуберкулезных препаратах. Рассматриваются данные о мутациях в ряде генов возбудителя, ассоциирующиеся или связанные с резистентностью к этим лекарственным препаратам. В обзор включены данные из 67 публикаций результатов исследований, систематических обзоров и электронных ресурсов.

Ключевые слова:

Mycobacterium tuberculosis

множественная лекарственная устойчивость

механизмы действия противотуберкулезных препаратов

механизмы резистентности к лекарственным препаратам

Авторы:

Шульгина М.В.

Институт медицинского образования ФГБУ «НМИЦ им. В.А. Алмазова» Минздрава РФ

ORCID: 0000-0002-3517-7848

Дата поступления:

28.01.2024

Дата принятия в печать:

13.02.2024

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