Нутритивная поддержка реанимационных больных: роль липидного компонента

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Нутритивная поддержка является важным компонентом лечения больных в критическом состоянии. Несвоевременная или неадекватная коррекция нарушений пищевого статуса сопровождается увеличением числа осложнений и показателей летальности у больных реанимационного профиля. Проведение нутритивной поддержки должно быть персонифицировано с учетом фазы критического состояния, основного заболевания, коморбидной патологии. Обеспечение больного энергетическими субстратами и пластическим материалом должно проводиться согласно действующим клиническим рекомендациям. Важным компонентом клинического питания является фармаконутриент ω-3-полиненасыщенные жирные кислоты, оказывающие противовоспалительное и иммуномодулирующее действие. Выявление новых свойств ω-3-полиненасыщенных жирных кислот, связанных с разрешением процессов воспаления, открывает многообещающие перспективы их применения. С целью изучения роли ω-3-полиненасыщенных жирных кислот в эффективности нутритивной поддержки у больных, находящихся в отделении реанимации и интенсивной терапии, выполнен анализ публикаций в медицинских базах eLibrary, PubMed, Medline (2005—2024 гг.). На основе полученных данных представлена доказательная база позитивных эффектов клинического питания с применением препаратов, в состав которых входят ω-3-полиненасыщенные жирные кислоты, у больных сепсисом, при остром повреждении легких, полиорганной недостаточности, новой коронавирусной инфекции.

Ключевые слова:

нутритивная поддержка

критическое состояние

ω-3-полиненасыщенные жирные кислоты

ω-3-ПНЖК

Авторы:

Пасечник И.Н.

ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента Российской Федерации

ORCID: 0000-0002-8121-4160

Талызин П.А.

ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента Российской Федерации;
ГБУЗ города Москвы «Городская клиническая больница им. М.Е. Жадкевича Департамента здравоохранения города Москвы»

ORCID: 0000-0001-8333-8354

Скобелев Е.И.

ORCID: 0000-0003-2815-5277

Дата поступления:

28.02.2024

Дата принятия в печать:

13.03.2024

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