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A.N. Kazyulin

Russian University of Medicine

A.Yu. Goncharenko

Russian University of Medicine

E.E. Pavleeva

Russian University of Medicine

I.Yu. Lyubozhnova

Russian University of Medicine

I.E. Kalyagin

Russian University of Medicine

Understanding similarities and differences of irritable bowel syndrome and conditions with IBS-like symptoms

Authors:

A.N. Kazyulin, A.Yu. Goncharenko, E.E. Pavleeva, I.Yu. Lyubozhnova, I.E. Kalyagin

More about the authors

Journal: Russian Journal of Evidence-Based Gastroenterology. 2024;13(1): 66‑78

DOI: 10.17116/dokgastro20241301166

Views: 343

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Table of contents

UNDERSTANDING SIMILARITIES AND DIFFERENCES OF IRRITABLE BOWEL SYNDROME AND CONDITIONS WITH IBS-LIKE SYMPTOMS
UNDERSTANDING SIMILARITIES AND DIFFERENCES OF IRRITABLE BOWEL SYNDROME AND CONDITIONS WITH IBS-LIKE SYMPTOMS

To cite this article:

Kazyulin AN, Goncharenko AYu, Pavleeva EE, Lyubozhnova IYu, Kalyagin IE. Understanding similarities and differences of irritable bowel syndrome and conditions with IBS-like symptoms. Russian Journal of Evidence-Based Gastroenterology. 2024;13(1):66‑78. (In Russ.)
https://doi.org/10.17116/dokgastro20241301166

Здоровье щитовидной железы – 2024
Перекрестки терапевтических проблем
Доказательная гастроэнтерология: pro et contra
Актуальные вопросы педиатрической практики
Подписка 2024, 2 полугодие
NN - давайте знакомится (08.04.2024)
Использование инфографики авторами научных работ
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OBJECTIVE

To analyze existing literature to identify similarities and differences in the epidemiological, clinical, diagnostic, and therapeutic aspects of irritable bowel syndrome (IBS) and conditions with IBS-like symptoms.

KEY POINTS

The review explores the similarities and differences among various conditions, including celiac disease, non-celiac gluten sensitivity, wheat allergy, increased non-gluten alpha-amylase/trypsin inhibitors, nickel allergic contact mucositis, consumption of high FODMAP foods, lactose intolerance, small intestinal bacterial overgrowth syndrome, inflammatory bowel diseases in remission, chronic pancreatitis, and gynecological disorders. Analysis of clinical studies has led to several hypotheses indicating that conditions with IBS-like symptoms share common features and pathogenesis with conditions with IBS-like symptoms, such as increased intestinal permeability, mucosal mediator release, upregulation of proinflammatory cytokines, neurogenic gut dysfunction, and disruption of the brain-gut axis.

CONCLUSION

It is currently postulated that using new diagnostic tools is advisable for identifying conditions with IBS-like symptoms in patients. The common pathogenesis suggests the potential use of a single therapeutic approach for patients with IBS and those with similar symptoms.

Keywords:

irritable bowel syndrome
IBS-like symptoms
FODMAP
intestinal permeability
brain-gut axis

Authors:

A.N. Kazyulin

Russian University of Medicine

A.Yu. Goncharenko

Russian University of Medicine

E.E. Pavleeva

Russian University of Medicine

I.Yu. Lyubozhnova

Russian University of Medicine

I.E. Kalyagin

Russian University of Medicine

Received:

14.12.2023

Accepted:

06.01.2024

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