Гиперпролиферативные заболевания женских половых органов и микробиота кишечника: эндометриоз, миома матки, гиперплазия эндометрия

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Микробиота — это совокупность микроорганизмов, присутствующих в определенной среде, которые участвуют в гемостазе организма. Большое число исследований посвящено изучению микробиома матки и его роли в развитии гинекологических заболеваний. На сегодняшний день существенное внимание уделяется изучению влияния микробиоты кишечника на состояние здоровья женщин, в частности на развитие гиперпластических процессов эндометрия. Более того, изучение микробиома кишечника является многообещающим в плане разработки терапевтических методов лечения гинекологических заболеваний.

Ключевые слова:

кишечная микрофлора

гиперплазия

миома

микробиом

эндометриоз

Авторы:

Адамян Л.В.

ГБОУ ВПО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России

ORCID: 0000-0002-3253-4512

Припутневич Т.В.

ФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. акад. В.И. Кулакова» Минздрава России

ORCID: 0000-0002-4126-9730

Пивазян Л.Г.

ORCID: 0000-0002-6844-3321

Мурватова К.К.

ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет)

ORCID: 0000-0002-3245-6948

Григорян И.Э.

ORCID: 0000-0003-4675-9568

Дата поступления:

03.06.2023

Дата принятия в печать:

24.06.2023

Список литературы:

Адамян Л.В., Припутневич Т.В., Григорян И.Э., Гаврилова Т.Ю., Саркисян Р.М., Антонова А.А. Современные представления о микробиоте эндометрия. Проблемы репродукции. 2022;28(6):159-163. https://doi.org/10.17116/repro202228061159
Адамян Л.В., Припутневич Т.В., Гаврилова Т.Ю., Григорян И.Э. Миома матки и микробиота эндометрия: имеется ли взаимосвязь? Проблемы репродукции. 2022;28(6):164-169. https://doi.org/10.17116/repro20222806116
Адамян Л.В., Припутневич Т.В., Григорян И.Э., Соколов А.Д. Вклад микробиоты эндометрия в развитие эндометриоза и аденомиоза у женщин репродуктивного возраста. Проблемы репродукции. 2022;28(6):170-174. https://doi.org/10.17116/repro202228061170
Baker JM, Al-Nakkash L, Herbst-Kralovetz MM. Estrogen-gut microbiome axis: Physiological and clinical implications. Maturitas. 2017;103:45-53. https://doi.org/10.1016/j.maturitas.2017.06.025
Leonardi M, Hicks C, El-Assaad F, El-Omar E, Condous G. Endometriosis and the microbiome: a systematic review. BJOG. 2020;127(2):239-249. https://doi.org/10.1111/1471-0528.15916
Salliss ME, Farland LV, Mahnert ND, Herbst-Kralovetz MM. The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain. Human Reproduction Update. 2021;28(1):92-131. https://doi.org/10.1093/humupd/dmab035
Flores R, Shi J, Fuhrman B, Xu X, Veenstra TD, Gail MH, Gajer P, Ravel J, Goedert JJ. Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study. Journal of Translational Medicine. 2012;10:253. https://doi.org/10.1186/1479-5876-10-253
Graham ME, Herbert WG, Song SD, Raman HN, Zhu JE, Gonzalez PE, Walther-António MRS, Tetel MJ. Gut and vaginal microbiomes on steroids: implications for women’s health. Trends in Endocrinology and Metabolism: TEM. 2021;32(8):554-565. https://doi.org/10.1016/j.tem.2021.04.014
Ervin SM, Li H, Lim L, Roberts LR, Liang X, Mani S, Redinbo MR. Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens. The Journal of Biological Chemistry. 2019;294(49):18586-18599. https://doi.org/10.1074/jbc.RA119.010950
Plottel CS, Blaser MJ. Microbiome and malignancy. Cell Host and Microbe. 2011;10:324-335. https://doi.org/10.1016/j.chom.2011.10.003
Chadchan SB, Singh V, Kommagani R. Female reproductive dysfunctions and the gut microbiota. Journal of Molecular Endocrinology. 2022;69(3):81-94. https://doi.org/10.1530/JME-21-0238
Franasiak JM, Scott RT. Introduction: microbiome in human reproduction Fertility and Sterility. 2015;104(6):1341-1343. https://doi.org/10.1016/j.fertnstert.2015.10.021
Chen KL, Madak-Erdogan Z. Estrogen and Microbiota Crosstalk: Should We Pay Attention? Trends in Endocrinology and Metabolism: TEM. 2016;27(11):752-755. https://doi.org/10.1016/j.tem.2016.08.001
Leeners B, Geary N, Tobler PN, Asarian L. Ovarian hormones and obesity. Human Reproduction Update. 2017;23(3):300-321. https://doi.org/10.1093/humupd/dmw045
Laschke MW, Menger MD. The gut microbiota: a puppet master in the pathogenesis of endometriosis. American Journal of Obstetrics and Gynecology. 2016;215(1):68.e1-68.e684. https://doi.org/10.1016/j.ajog.2016.02.036
Qi X, Yun C, Pang Y, Qiao J. The impact of the gut microbiota on the reproductive and metabolic endocrine system. Gut Microbes. 2021;13(1):1-21. https://doi.org/10.1080/19490976.2021.1894070
Lan J, Chen C, Chen L, Liu P. Intestinal microflora provides biomarkers for infertile women with endometrial polyps. Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 2022;27(6):579-586. https://doi.org/10.1080/1354750X.2022.2077445
Mao X, Peng X, Pan Q, Zhao X, Yu Z, Xu D. Uterine Fibroid Patients Reveal Alterations in the Gut Microbiome. Frontiers in Cellular and Infection Microbiology. 2022;12:863594. https://doi.org/10.3389/fcimb.2022.863594
Wang W, Li Y, Wu Q, Pan X, He X, Ma X. High-throughput sequencing study of the effect of transabdominal hysterectomy on intestinal flora in patients with uterine fibroids. BMC Microbiology. 2020;20(1):1-11. https://doi.org/10.1186/s12866-020-01779-7
Yang Q, Ciebiera M, Bariani MV, Ali M, Elkafas H, Boyer TG, Al-Hendy A. Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment. Endocrine Reviews. 2022;43(4):678-719. https://doi.org/10.1210/endrev/bnab039
Martin DH. The microbiota of the vagina and its influence on women’s health and disease. American Journal of Medical Sciences. 2012;343(1):2-9. https://doi.org/10.1097/MAJ.0b013e31823ea228
Talwar C, Singh V, Kommagani R. The gut microbiota: A double edge sword in endometriosis. Biology of Reproduction. 2022;107(4):881-901. https://doi.org/10.1093/biolre/ioac147
Nelson DB, Rockwell LC, Prioleau MD, Goetzl L. The role of the bacterial microbiota on reproductive and pregnancy health. Anaerobe. 2016;42:67-73. https://doi.org/10.1016/j.anaerobe.2016.09.001
Ilangavan K, Kalu E. High prevalence of endometriosis in infertile women with normal ovulation and normospermic partners. Fertility and Sterility. 2010;93(3):e10. https://doi.org/10.1016/j.fertnstert.2009.11.027
Goenka L, George M, Sen M. A peek into the drug development scenario of endometriosis — A systematic review. Biomedicine and Pharmacotherapy. 2017;90:575-585. https://doi.org/10.1016/j.biopha.2017.03.092
Svensson A, Brunkwall L, Roth B, Orho-Melander M, Ohlsson B. Associations Between Endometriosis and Gut Microbiota. Reproductive Sciences. 2021;28(8):2367-2377. https://doi.org/10.1007/s43032-021-00506-5
Shan J, Ni Z, Cheng W, Zhou L, Zhai D, Sun S, Yu C. Gut microbiota imbalance and its correlations with hormone and inflammatory factors in patients with stage 3/4 endometriosis. Archives of Gynecology and Obstetrics. 2021;304(5):1363-1373. https://doi.org/10.1007/s00404-021-06057-z
Huang J, Shan W, Li F, Wang Z, Cheng J, Lu F, Guo E, Beejadhursing R, Xiao R, Liu C, Yang B, Li X, Fu Y, Xi L, Wang S, Ma D, Chen G, Sun C. Fecal microbiota transplantation mitigates vaginal atrophy in ovariectomized mice. Aging. 2021;13(5):7589-7607. https://doi.org/10.18632/aging.202627
Qin R, Tian G, Liu J, Cao L. The gut microbiota and endometriosis: From pathogenesis to diagnosis and treatment. Frontiers in Cellular and Infection Microbiology. 2022;12:1069557. https://doi.org/10.3389/fcimb.2022.1069557
Thomas RM, Jobin C. The Microbiome and Cancer: Is the ‘Oncobiome’ Mirage Real? Trends in Cancer. 2015;1(1):24-35. https://doi.org/10.1016/j.trecan.2015.07.005
Wallace AE, Gibson DA, Saunders PT, Jabbour HN. Inflammatory events in endometrial adenocarcinoma. The Journal of Endocrinology. 2010;206(2):141-157. https://doi.org/10.1677/JOE-10-0072
Borella F, Carosso AR, Cosma S, Preti M, Collemi G, Cassoni P, Bertero L, Benedetto C. Gut Microbiota and Gynecological Cancers: A Summary of Pathogenetic Mechanisms and Future Directions. ACS Infectious Diseases. 2021;7(5):987-1009. https://doi.org/10.1021/acsinfecdis.0c00839
Laniewski P, Ilhan ZE, Herbst-Kralovetz MM. The microbiome and gynaecological cancer development, prevention and therapy. Nature Reviews. Urology. 2020;17(4):232-250. https://doi.org/10.1038/s41585-020-0286-z
Lev-Sagie A, Goldman-Wohl D, Cohen Y, Dori-Bachash M, Leshem A, Mor U, Strahilevitz J, Moses AE, Shapiro H, Yagel S, Elinav E. Vaginal microbiome transplantation in women with intractable bacterial vaginosis. Nature Medicine. 2019;25(10):1500-1504. https://doi.org/10.1038/s41591-019-0600-6
Molina NM, Sola-Leyva A, Saez-Lara MJ, Plaza-Diaz J, Tubić-Pavlović A, Romero B, Clavero A, Mozas-Moreno J, Fontes J, Altmäe S. New Opportunities for Endometrial Health by Modifying Uterine Microbial Composition: Present or Future? Biomolecules. 2020;10(4):593. https://doi.org/10.3390/biom10040593
Chadchan SB, Popli P, Ambati CR, Tycksen E, Han SJ, Bulun SE, Putluri N, Biest SW, Kommagani R. Gut microbiota-derived short-chain fatty acids protect against the progression of endometriosis. Life Science Alliance. 2021;4(12):e202101224. https://doi.org/10.26508/lsa.202101224

Nguyen Manh T, Bui Van N, Le Thi H, Vo Hoang L, Nguyen Si Anh H, Trinh Thi Thu H, Nguyen Xuan T, Vu Thi N, Minh LB, Chu DT. Pregnancy with heart disease: maternal outcomes and risk factors for fetal growth restriction. International Journal of Environmental Research and Public Health. 2019;16(12):2075. https://doi.org/10.3390/ijerph16122075

Hart MV, Morton MJ, Hosenpud JD, Metcalfe J. Aortic function during normal human pregnancy. American Journal of Obstetrics and Gynecology. 1986;154(4):887-891. https://doi.org/10.1016/0002-9378(86)90477-1

Bons LR, Roos-Hesselink JW. Aortic disease and pregnancy. Current Opinion in Cardiology. 2016;31(6):611-617. https://doi.org/10.1097/HCO.0000000000000336

Little B. Water and electrolyte balance during pregnancy. Anesthesiology. 1965;26:408. https://doi.org/10.1097/00000542-196507000-00005

Kumar P, Magon N. Hormones in pregnancy. Nigerian Medical Journal. 2012;53(4):179-183. https://doi.org/10.4103/0300-1652.107549

Napso T, Yong HEJ, Lopez-Tello J and Sferruzzi-Perri AN. The Role of Placental Hormones in Mediating Maternal Adaptations to Support Pregnancy and Lactation. Frontiers in Physiology. 2018;9:1091. https://doi.org/10.3389/fphys.2018.01091

Van Hagen IM, Roos-Hesselink JW. Aorta pathology and pregnancy. Best Practice and Research. Clinical Obstetrics and Gynaecology. 2014;28(4):537-550.

Warnes CA. Pregnancy and Delivery in Women with Congenital Heart Disease. Circulation Journal. 2015;(79):1416-1421. https://doi.org/10.1253/circj.CJ-15-0572

Wald RM, Silversides CK, Kingdom J, Toi A, Lau CS, Mason J, Colman JM, Sermer M, Siu SC. Maternal cardiac output and fetal doppler predict adverse neonatal outcomes in pregnant women with heart disease. Journal of the American Heart Association. 2015;4(11):e002414. https://doi.org/10.1161/JAHA.115.002414

Verlohren S, Melchiorre K, Khalil A, Thilaganathan.B. Uterine artery Doppler, birth weight and timing of onset of pre-eclampsia: providing insights into the dual etiology of late-onset pre-eclampsia. Ultrasound in Obstetrics and Gynecology. 2014;44(3):293-298. https://doi.org/10.1002/uog.13310

Thalmann M, Sodeck G.H, Domanovits H, Grassberger M, Loewe C, Michael Grimm, Czerny M. Acute type A aortic dissection and pregnancy: a population-based study. European Journal of Cardio-Thoracic Surgery. 2011;39(Issue 6):159-e163. https://doi.org/10.1016/j.ejcts.2010.12.070

Friel LA. Troubles Cardiaques Pendant la Grossesse University of Texas Health Medical School at Houston. McGovern Medical School;2017.

Niwa K, Perloff JK, Bhuta SM, Laks H, Drinkwater DC, Child JS, Miner PD. Structural abnormalities of great arterial walls in congenital heart disease: light and electron microscopic analyses. Circulation. 2001;103(3):393-400. https://doi.org/10.1161/01.cir.103.3.393

Oliver JM, Gallego P, Gonzalez A, Aroca A, Bret M, Mesa JM. Risk factors for aortic complications in adults with coarctation of the aorta. Journal of the American College of Cardiology. 2004;44(8):1641-1647. https://doi.org/10.1016/j.jacc.2004.07.037

Krywko DM, King KC. Aortocaval Compression Syndrome. StatPearls Publishing. Aug 08, 2022.

Ohlson L. Effects of the pregnant uterus on the abdominal aorta and its branches. Acta Radiologica: Diagnosis.1978;19(2):369-376. https://doi.org/10.1177/028418517801900212

Saeki N, Taguchi S, Kawamoto M. Successful management ofa patient with Marfan syndrome complicated with acute aorticdissection using landiolol during cesarean section. Journal of Anesthesia. 2010;24(2):277-279. https://doi.org/10.1007/s00540-009-0859-8

Yuan Shi-Min. Bicuspid aortic valve in pregnancy. Taiwanese Journal of Obstetrics and Gynecology. 2014;53(4):476-480. https://doi.org/10.1016/j.tjog.2013.06.018

Kamel H, Roman MJ, Pitcher A, Devereux RB. Pregnancy and the Risk of Aortic Dissection or Rupture. A Cohort-Crossover Analysis. Circulation. 2016;134(7):527-533. https://doi.org/10.1161/CIRCULATIONAHA.116.021594

Yuan S-M. Aortic Dissection During Pregnancy: A Difficult Clinical Scenario. Clinical Cardiology. 2013;36(10):576-584. https://doi.org/10.1002/clc.22165

Wanga S, Silversides C, Dore A, de Waard V, Mulder B. Pregnancy and thoracic aortic disease: managing the risks. Canadian Journal of Cardiology. 2016;32(1):78-85. https://doi.org/10.1016/j.cjca.2015.09.003

Osol G, Ko NL, Mandalà M. Plasticity of the maternal vasculature during pregnancy. Annual Review of Physiology. 2019;81:89-111. https://doi.org/10.1146/annurev-physiol-020518-114435

Cherpak BV, Davydova YV, Kravchenko VI, Yaschuk NS, Siromakha SO, Lazoryshynets VV. Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy. Journal of Medicine and Life. 2022;15(2):208-213. https://doi.org/10.25122/jml-2021-0363

Connolly HM, Huston J 3rd, Brown RD Jr, Warnes CA, Ammash NM, Tajik AJ. Intracranial aneurysms in patients with coarctation of the aorta: a prospective magnetic resonance angiographic study of 100 patients. Mayo Clinic Proceedings. 2003;78(12):1491-1499. https://doi.org/10.4065/78.12.1491

Singh PK, Marzo A, Staicu C, William MG, Wilkinson I, Lawford PV, Rufenacht DA, Bijlenga P, Frangi AF, Hose R, Patel UJ, Coley SC. The Effects of Aortic Coarctation on Cerebral Hemodynamics and its Importance in the Etiopathogenesis of Intracranial Aneurysms. Journal of Vascular and Interventional Neurology. 2010;3(1):17-30.

Dias MS, Sekhar LN. Intracranial haemorrhage from aneurysms and arteriovenous malformations during pregnancy and the puerperium. Neurosurgery. 1990;27(6):855-865. https://doi.org/10.1097/00006123-199012000-00001

Mehrotra M, Mehrotra A, Nair A, Srivastava A, Sahu RN, Pradhan M, Kuma R. Intracranial hemorrhage from giant aneurysm in pregnancy: A rare association. Asian Journal of Neurosurgery. 2017; 12(1):142-144. https://doi.org/10.4103/1793-5482.145553

Miller HJ, Hinkley CM: Berry aneurysms in pregnancy: a 10 year report. Southern Medical Journal. 1970;63(3):279. https://doi.org/10.1097/00007611-197003000-00007

Kim YW, Neal D, Hoh BL. Cerebral Aneurysms in Pregnancy and Delivery: Pregnancy and Delivery Do Not Increase the Risk of Aneurysm Rupture. Neurosurgery. 2013;72(Issue 2):143-150. https://doi.org/10.1227/NEU.0b013e3182796af9

Stout KK, Daniels CJ, Aboulhosn JA, Bozkurt B, Broberg CS, Colman JM, Crumb SR, Dearani JA, Fuller S, Gurvitz M, Khairy P, Landzberg MJ, Saidi A, Valente AM, Van Hare GF. 2018 ACC/AHA guidelines on adult congenital heart disease: Executive summary: A report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. Circulation. 2019;139(14):637-697. https://doi.org/10.1161/CIR.0000000000000602

Ntiloudi D, Zegkos T, Bazmpani MA, Parcharidou D, Panagiotidis T, Hadjimiltiades S, Karvounis H, Giannakoulas G. Pregnancy outcome in women with congenital heart disease: A single-center experience. Hellenic Journal of Cardiology. 2018;59(3):155-159. https://doi.org/10.1016/j.hjc.2017.08.008

Pieper PG, Balci A, Aarnoudse JG, Kampman MA, Sollie KM, Groen H, Mulder BJ, Oudijk MA, Roos-Hesselink JW, Cornette J, van Dijk AP, Spaanderman ME, Drenthen W, van Veldhuisen DJ; ZAHARA II investigators. Uteroplacental blood flow, cardiac function, and pregnancy outcome in women with congenital heart disease. Circulation. 2013;128(23): 2478-2487. https://doi.org/10.1161/CIRCULATIONAHA.113.002810

Siegmund AS, Kampman MAM, Bilardo CM, Balci A, van Dijk APJ, Oudijk MA, Mulder BJM, Roos-Hesselink JW, Sieswerda GT, Koenen SV, Sollie-Szarynska KM, Ebels T, van Veldhuisen DJ, Pieper PG; ZAHARA investigators. Pregnancy in women with corrected aortic coarctation: uteroplacental doppler flow and pregnancy outcome. Journal of Cardiology. 2017;249:145-150. https://doi.org/10.1016/j.ijcard.2017.09.167

Avanzas P, García-Fernández M.A, Quiles J, Datino T, Moreno M. Pseudoaneurysm complicating aortic coarctation in a pregnant woman. International Journal of Cardiology. 2004;9(1):157-158. https://doi.org/10.1016/j.ijcard.2003.06.037

Мравян С.Р., Петрухин В.А., Пронина В.П., Вишнякова М.В., Абраменко А.С., Хапий Н.Х., Лысенко С Н. Течение беременности и родоразрешение пациенток, перенесших операцию по поводу коарктации аорты. Российский вестник акушера-гинеколога. 2014;14(6):49-54.

Иртюга О.Б., Мгдесян К.О., Моисеева О.М. Особенности ведения беременности и родов у пациенток с патологией аорты и аортального клапана. Российский кардиологический журнал. 2017;2:80-86.

Butalia S, Audibert F, Côté AM. Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy. Canadian Journal of Cardiology. 2018;(34):526-531. https://doi.org/10.1016/j.cjca.2018.02.021

Melchiorre K, Sharma R, Thilaganathan B. Cardiovascular implications in preeclampsia: an overview. Circulation. 2014;130:703-714. https://doi.org/10.1161/CIRCULATIONAHA.113.003664

Moore LG, Shriver M, Bemis L, Hickler B, Wilson M, Brutsaert T, Parra E, Vargas E. Maternal adaptation to high-altitude pregnancy: an experiment of nature — a review. Placenta. 2004;25(Suppl A): 60-71. https://doi.org/10.1016/j.placenta.2004.01.008

Ladouceur M, Benoit L, Radojevic J, Basquin A, Dauphin C, Hascoet S, Moceri P, Bredy C, Iserin L, Gouton M, Nizard J. Pregnancy Outcomes in Patients with Pulmonary Arterial Hypertension Associated with Congenital Heart Disease. Heart. 2017;103(4): 287-292. https://doi.org/10.1136/heartjnl-2016-310003

Knight M, Nair M, Tuffnell D, Shakespeare J, Kenyon S, Kurinczuk JJ, eds; on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care—Lessons Learned to Inform Maternity Care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2013–15. Oxford: National Perinatal Epidemiology Unit. University of Oxford, 2017

Ramlakhan KP, Tobler D, Greutmann M, Schwerzmann M, Baris L, Yetman AT, Nihoyannopoulos P, Manga P, Boersma E, Maggioni AP, Johnson MR, Hall R, Roos-Hesselink JW; ROPAC investigators group. On behalf of the ROPAC investigators group. Pregnancy outcomes in women with aortic coarctation. Heart. 2021;107(4): 290-298. https://doi.org/10.1136/heartjnl-2020-317513

WHO Recommendations for Prevention and Treatment of Pre-Eclampsia and Eclampsia. Geneva World Health Organization; 2011.

Ananth CV, Keyes KM, Wapner RJ. Pre-Eclampsia rates in the United States, 1980-2010: age-period-cohort analysis. BMJ. 2013;347:f6564. https://doi.org/10.1136/bmj.f6564

Boerma T, Ronsmans C, Melesse DY, Barros AJD, Barros FC, Juan L, Moller AB, Say L, Hosseinpoor AR, Yi M, de Lyra Rabello Neto D, Temmerman M. Global epidemiology of use of and disparities in caesarean sections. Lancet. 2018;392:1341-1348. https://doi.org/10.1016/S0140-6736(18)31928-7

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