Методы хирургической реконструкции конъюнктивы

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Реконструкция конъюнктивы играет ключевую роль в регенерации глазной поверхности при ее поражении и является неотъемлемой частью этого процесса. Травмы, химические, термические ожоги и множественные хирургические вмешательства могут серьезно нарушать целостность конъюнктивальной ткани и приводить к росту фиброзной ткани, рубцеванию сводов, их укорочению, а также другим осложнениям в виде трихиаза, эрозий и язв роговицы. При поражении обширной зоны конъюнктивы донорской ткани для замещения дефекта может быть недостаточно, и в таких случаях требуется применение больших по площади трансплантатов. Современные модификации хирургических методик и развивающаяся область тканевой инженерии, а также достижения в сфере исследования стволовых клеток предлагают многообещающие новые альтернативы для решения такого рода задач. В данном обзоре рассматриваются существующие на сегодняшний день хирургические методы реконструкции конъюнктивы.

Ключевые слова:

конъюнктива

реконструкция конъюнктивы

тканевая инженерия

аутотрансплантация

амниотическая мембрана

биополимеры

Авторы:

Криволапова Д.А.

ФГБНУ «Научно-исследовательский институт глазных болезней им. М.М. Краснова»

ORCID: 0000-0001-6974-7872

Андреев А.Ю.

ФГБНУ «Научно-исследовательский институт глазных болезней им. М.М. Краснова»

ORCID: 0000-0002-0267-9040

Осидак Е.О.

ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Д. Рогачева» Минздрава России

ORCID: 0000-0003-2549-4011

Будникова Е.А.

ФГБНУ «Научно-исследовательский институт глазных болезней им. М.М. Краснова»

ORCID: 0000-0001-7721-7652

Дата поступления:

31.03.2023

Дата принятия в печать:

19.07.2023

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