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Kosyrkova A.V.

Burdenko Neurosurgical Center

Goryainov S.A.

Burdenko Neurosurgical Center;
Kant Baltic Federal University

Kravchuk A.D.

Burdenko Neurosurgical Center

Aristov A.A.

Burdenko Neurosurgical Center

Batalov A.I.

Burdenko Neurosurgical Center

Zakharova N.E.

Burdenko Neurosurgical Center

Polupan A.A.

Burdenko Neurosurgical Center

Shishkina L.V.

Burdenko Neurosurgical Center

Shugai S.V.

Burdenko Neurosurgical Center

Metastatic brain lesion following gastrointestinal stromal tumor of the stomach complicated by coma.( A case report and literature review)

Authors:

Kosyrkova A.V., Goryainov S.A., Kravchuk A.D., Aristov A.A., Batalov A.I., Zakharova N.E., Polupan A.A., Shishkina L.V., Shugai S.V.

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Journal: Burdenko's Journal of Neurosurgery. 2023;87(4): 93‑100

DOI: 10.17116/neiro20238704193

Views: 1330

Downloaded: 28

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To cite this article:

Kosyrkova AV, Goryainov SA, Kravchuk AD, et al. . Metastatic brain lesion following gastrointestinal stromal tumor of the stomach complicated by coma.( A case report and literature review). Burdenko's Journal of Neurosurgery. 2023;87(4):93‑100. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20238704193

Подписка 2025-2 (Burdenko's Journal of Neurosurgery)
 
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The authors present an extremely rare case of metastatic brain lesion in a patient with gastrointestinal stromal tumor of the stomach. There are literature data on 23 cases of metastatic lesions of the brain, skull and soft tissues of the head in similar patients. Atypical localization of metastases can lead to some diagnostic difficulties, unreasonable cancellation of chemotherapy and delayed surgical treatment. A feature of our observation was postoperative coma determined by the features of the underlying disease.

Keywords:

gastrointestinal tumor
GIST
metastases
Wernicke’s encephalitis
paraneoplastic syndrome

Authors:

Kosyrkova A.V.

Burdenko Neurosurgical Center

Goryainov S.A.

Burdenko Neurosurgical Center;
Kant Baltic Federal University

Kravchuk A.D.

Burdenko Neurosurgical Center

Aristov A.A.

Burdenko Neurosurgical Center

Batalov A.I.

Burdenko Neurosurgical Center

Zakharova N.E.

Burdenko Neurosurgical Center

Polupan A.A.

Burdenko Neurosurgical Center

Shishkina L.V.

Burdenko Neurosurgical Center

Shugai S.V.

Burdenko Neurosurgical Center

Received:

05.02.2023

Accepted:

19.05.2023

List of references:

  1. O’Halloran PJ, Hannon AM, Bartels C, McCawley N, Agha A, Brett F, Leader M, Broe P, Javadpour M. Gastrointestinal stromal tumor metastases to the pituitary: a rare entity. British Journal of Neurosurgery. 2017;31(5):603-604.  https://doi.org/10.3109/02688697.2016.1173194
  2. Barrière J, Thariat J, Vandenbos F, Bondiau PY, Peyrottes I, Peyrade F. Diplopia as the first symptom of an aggressive metastatic rectal stromal tumor. Onkologie. 2009;32(6):345-347.  https://doi.org/10.1159/000215712
  3. Gerin F, Baloglu O, Morgan JA, Kesari S. Central nervous system metastases from imatinib mesylate resistant gastrointestinal stromal tumor. Journal of Neuro-Oncology. 2007;82(2):227-228.  https://doi.org/10.1007/s11060-006-9277-z
  4. Inage Y, Yamabe K, Yamamoto T, Sato Y, Ishikawa S, Onizuka M, Yoshida K. Resection for pulmonary metastasis of gastrointestinal stromal tumor of the stomach at 10 years after gastrectomy; report of a case. Kyobu Geka. 2002;55(10):907-911. 
  5. Badri M, Chabaane M, Gader G, Bahri K, Zammel I. Cerebellar metastasis of gastrointestinal stromal tumor: A case report and review of the literature. International Journal of Surgery Case Reports. 2018;42:165-168.  https://doi.org/10.1016/j.ijscr.2017.12.009
  6. Baeg MK, Bae SH, Lee KH, Kim J, Park IS, Jin JY. Diplopia as a presenting symptom in a gastric gastrointestinal stromal tumor. Japanese Journal of Clinical Oncology. 2011;41(2):265-268.  https://doi.org/10.1093/jjco/hyq176
  7. DeVita VT, Lawrence TS, Rosenberg SA. DeVita, Hellman, and Rosenberg’s Cancer : Principles & Practice of Oncology. Ed. DeVita VT, Lawrence TS, Rosenberg SA. 11th edition. Philadelphia: Wolters Kluwer; 2019.
  8. Prablek M, Srinivasan VM, Srivatsan A, Holdener S, Oneissi M, Heck KA, Jalali A, Mandel J, Viswanathan A, Patel AJ. Gastrointestinal stromal tumor with intracranial metastasis: case presentation and systematic review of literature. BMC Cancer. 2019;19(1):1119. https://doi.org/10.1186/s12885-019-6316-7
  9. Wong CS, Chu YC. Intra-cranial metastasis of gastrointestinal stromal tumor. Chinese Medical Journal. 2011;124(21):3595-3597.
  10. Sato K, Tanaka T, Kato N, Ishii T, Terao T, Murayama Y. Metastatic cerebellar gastrointestinal stromal tumor with obstructive hydrocephalus arising from the small intestine: a case report and review of the literature. Case Reports in Oncological Medicine. 2014;2014:343178. https://doi.org/10.1155/2014/343178
  11. Kaku S, Tanaka T, Ohtuka T, Seki K, Sawauchi S, Numoto RT, Murakami S, Komine K, Abe T. Perisacral gastrointestinal stromal tumor with intracranial metastasis. Case report. Neurologia Medico-Chirurgica. 2006;46(5):254-257.  https://doi.org/10.2176/nmc.46.254
  12. Takeuchi H, Koike H, Fujita T, Tsujino H, Iwamoto Y. Sunitinib treatment for multiple brain metastases from jejunal gastrointestinal stromal tumor: case report. Neurologia Medico-Chirurgica. 2014;54(8):664-669.  https://doi.org/10.2176/nmc.cr2012-0426
  13. Hamada S, Itami A, Watanabe G, Nakayama S, Tanaka E, Hojo M, Yoshizawa A, Hirota S, Sakai Y. Intracranial metastasis from an esophageal gastrointestinal stromal tumor. Internal Medicine. 2010;49(8):781-785.  https://doi.org/10.2169/internalmedicine.49.3124
  14. Jagannathan JP, Ramaiya NH, Shinagare AB, Hornick JL, George S. Intracranial metastasis from pediatric GI stromal tumor. Journal of Clinical Oncology. 2012;30(10):122-125.  https://doi.org/10.1200/JCO.2011.38.1798
  15. Hughes B, Yip D, Goldstein D, Waring P, Beshay V, Chong G. Cerebral relapse of metastatic gastrointestinal stromal tumor during treatment with imatinib mesylate: case report. BMC Cancer. 2004;4:74.  https://doi.org/10.1186/1471-2407-4-74
  16. Ishi Y, Nakayama N, Kobayashi H, Yamaguchi S, Terasaka S, Houkin K. Successful Removal of a Metastatic Gastrointestinal Stromal Tumor in the Craniovertebral Junction using an Occipital Artery to Posterior Inferior Cerebellar Artery Bypass. Case Reports in Neurology. 2014;6(2):139-143.  https://doi.org/10.1159/000362867
  17. Carvalho J, Teixeira M, Silva FT, Esteves A, Ribeiro C, Guerra D. Esophageal Gastrointestinal Stromal Tumor with Rare Intracranial Metastasis. Case Reports in Gastrointestinal Medicine. 2020;2020:8842006. https://doi.org/10.1155/2020/8842006
  18. Naoe H, Kaku E, Ido Y, Gushima R, Maki Y, Saito H, Yokote S, Gushima R, Nonaka K, Hoshida Y, Murao T, Ozaki T, Yokomine K, Tanaka H, Nagahama H, Sakurai K, Tanaka M, Iyama K, Baba H, Sasaki Y. Brain metastasis from gastrointestinal stromal tumor: a case report and review of the literature. Case Reports in Gastrointerology. 2011;5(3):583-589.  https://doi.org/10.1159/000333403
  19. Janku F, Kidney D, Coyne J. Unusual presentation of gastrointestinal stromal tumor with early cerebral involvement. Irish Journal of Medical Science. 2011;180(3):765-766.  https://doi.org/10.1007/s11845-010-0591-2
  20. Drazin D, Spitler K, Jeswani S, Shirzadi A, Bannykh S, Patil C. Multiple intracranial metastases from a gastric gastrointestinal stromal tumor. Journal of Clinical Neuroscience. 2013;20(3):471-473.  https://doi.org/10.1016/j.jocn.2012.02.037
  21. Leske H, Rushing E, Bernays R. A 40-Year-Old Female with Dural-Based Lesions. Brain Pathology. 2018;28(2):299-300.  https://doi.org/10.1111/bpa.12588
  22. Kim YJ, Lee WJ, Won CH, Choi JH, Lee MW. Metastatic Cutaneous Duodenal Gastrointestinal Stromal Tumor: A Possible Clue to Multiple Metastases. Annals of Dermatology. 2018;30(3):345-347.  https://doi.org/10.5021/ad.2018.30.3.345
  23. Gupta S, Bi WL, Dunn IF. Metastatic Gastrointestinal Stromal Tumor to the Skull. World Neurosurgery. 2016;89:725.e11-16.  https://doi.org/10.1016/j.wneu.2016.01.019
  24. Brooks BJ, Bani JC, Fletcher CD, Demeteri GD. Challenges in oncology. Case 4. Response of metastatic gastrointestinal stromal tumor including CNS involvement to imatinib mesylate (STI-571). Journal of Clinical Oncology. 2002;20(3):870-872.  https://doi.org/10.1200/JCO.2002.20.3.870
  25. Ishiguro T, Nitta M, Komori T, Maruyama T, Muragaki Y, Kawamata T. Transient Focal Magnetic Resonance Imaging Abnormalities After Status Epilepticus Showed 11C-Methionine Uptake with Positron Emission Tomography in a Patient with Cerebral Cavernous Malformation. World Neurosurgery. 2018;114:43-46.  https://doi.org/10.1016/j.wneu.2018.03.020
  26. Wlock R, Patel K, Patel M, Tanase A. Leptomeningeal Carcinomatosis Secondary to a Gastrointestinal Stromal Tumor. Cureus. 2021;13(7):e16212. https://doi.org/10.7759/cureus.16212
  27. Taketa T, Ohigashi S, Suzuki K, Sudo K, Shiozaki H, Suzuki A, Blum MA, Ajani JA, Onodera H. Paraneoplastic neurological syndromes associated with gastric cancer: a case report and review of the literature. Clinical Journal of Gastroenterology. 2012;5(5):355-360.  https://doi.org/10.1007/s12328-012-0328-z

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