Роль жировой ткани в возникновении и прогрессировании колоректального рака

Авторы:
  • Р. А. Москаленко
    Сумский государственный университет, Медицинский институт МОН Украины, Сумы, Украина
  • Ю. С. Корнева
    ФГБОУ ВО «Смоленский государственный медицинский университет» Минздрава России, Смоленск, Россия; ОГБУЗ «Смоленcкий областной институт патологии», Смоленск, Россия
Журнал: Архив патологии. 2019;81(1): 52-56
Просмотрено: 965 Скачано: 6
Представлены современные данные литературы о взаимосвязи и патогенетических механизмах влияния жировой ткани на канцерогенез колоректального рака (КРР). Рассматриваются аспекты изменения жировой ткани и микроокружения самой опухоли, в том числе под влиянием биологически активных веществ, выделяемых адипоцитами; отличия подкожного и висцерального жира и их значение в становлении и прогрессировании КРР, а также роль стволовых клеток жировой ткани. Понимание данных механизмов влияния жировой ткани на КРР поможет не только профилактике данного заболевания, но и поиску новых терапевтических мишеней.
Ключевые слова:
  • колоректальный рак
  • жировая ткань
  • висцеральный жир
  • стволовые клетки жировой ткани

КАК ЦИТИРОВАТЬ:

Москаленко Р.А., Корнева Ю.С. Роль жировой ткани в возникновении и прогрессировании колоректального рака. Архив патологии. 2019;81(1):52-56. https://doi.org/10.17116/patol20198101152

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